Director dealings: AstraZeneca CFO ups stake
AstraZeneca chief financial officer Marc Dunoyer purchased 8,500 ordinary shares in the FTSE 100-listed pharmaceuticals outfit on Tuesday.
AstraZeneca
11,998.00p
09:05 26/04/24
FTSE 100
8,114.66
09:05 26/04/24
FTSE 350
4,456.07
09:05 26/04/24
FTSE All-Share
4,409.36
09:05 26/04/24
Pharmaceuticals & Biotechnology
22,730.58
09:05 26/04/24
Dunoyer, who took over as CFO back in October 2013, acquired the shares at an average price of 5,800p each, for a total value of £493,000, the company said in a statement.
AstraZeneca and its partner Daiichi Sankyo Company announced positive top-line results for the pivotal phase 2 ‘DESTINY-Breast01’ trial of trastuzumab deruxtecan (DS-8201) on the following day.
The group said the HER2-targeting antibody drug conjugate (ADC) and potential new medicine was evaluated in patients with HER2-positive, unresectable and/or metastatic breast cancer previously treated with trastuzumab emtansine.
It said the response rate in DESTINY-Breast01, as assessed by an independent review committee, confirmed in a “heavily-pretreated, global” patient population the “unprecedented” clinical activity in the recently-published phase 1 trial.
The safety and tolerability profile of trastuzumab deruxtecan was also consistent with previous experience.
As of 1620 BST, AstraZeneca shares were up 0.88% to 5,851p.
Top Director Buys
AstraZeneca (AZN)
Director name: Mr Marc Dunoyer
Amount purchased: 8,500 @ 5,800.00p
Value: £493,000
VPC Specialty Lending Investments (VSL)
Director name: Mr Richard Levy
Amount purchased: 73,383 @ 72.00p
Value: £52,836
Mereo Biopharma Group (MPH)
Director name: Mr Anders Ekblom
Amount purchased: 46,700 @ 109.20p
Value: £50,996
Drax Group (DRX)
Director name: Mr Andy Skelton
Amount purchased: 15,000 @ 331.32p
Value: £49,698
International Personal Finance (IPF)
Director name: Mr Bronwyn Syiek
Amount purchased: 20,000 @ 176.25p
Value: £35,250
Domino's Pizza Group (DOM)
Director name: Mr David Bauernfeind
Amount purchased: 12,000 @ 260.38p
Value: £31,246
International Personal Finance (IPF)
Director name: Mr John Mangelaars
Amount purchased: 15,000 @ 174.35p
Value: £26,152
NMC Health (NMC)
Director name: Mr Mark Tompkins
Amount purchased: 642 @ 2,849.23p
Value: £18,292
EnQuest (ENQ)
Director name: Mr Helmut Langanger
Amount purchased: 87,302 @ 20.00p
Value: £17,460
Top Director Sells
Serco Group (SRP)
Director name: Mr Rupert Soames
Amount sold: 544,541 @ 124.97p
Value: £680,513
Serco Group (SRP)
Director name: Mr Angus Cockburn
Amount sold: 283,516 @ 124.97p
Value: £354,310
Serco Group (SRP)
Director name: Mr David Eveleigh
Amount sold: 18,629 @ 124.97p
Value: £23,281
NMC Health (NMC)
Director name: Mr Mark Tompkins
Amount sold: 642 @ 2,846.24p
Value: £18,273