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London's FTSE 100 ended the week 229. 08 points higher at 7,582. 48.
London's FTSE 250 was roughly flat, edging 0. 02% lower to 21,660. 78 in afternoon trade on Friday as TBC Bank led the fallers.
European stocks were firmer at noon on Friday, as comments from US Treasury Secretary Steven Mnuchin ignited Sino-US trade hopes, while German consumer sentiment missed expectations.
Shares of Physiomics leapt on Friday after it signed up to a £250,000 tranche of projects with pharmaceutical giant Merck and said trading was in line with expectations.
Brexit-related factory closures led to a 16. 5% slump in November UK car production, according to figures released on Friday.
European stocks rose on Friday morning, as comments from US Treasury Secretary Steven Mnuchin increased Sino-US trade optimism, while German consumer sentiment missed expectations.
AstraZeneca on Friday said it had agreed to sell the commercial rights to Arimidex (anastrozole) and Casodex (bicalutamide) to Juvisé Pharmaceuticals in several European, African and other countries.
London's FTSE 100 was up by 0. 39% at 7,570. 07 in afternoon trade on Thursday, with Flutter Entertainment leading the index higher.
London's FTSE 250 was up by 0. 07% at 21,679. 21 in afternoon trade on Thursday, with real estate services provider Savills leading the index higher.
Shares of Bilby surged on Thursday as it claimed to have resolved issues relating to its P&R business but reported a dive in interim profits.
European stocks were little changed at noon on Thursday, as Washington's impeachment drama and rate changes in Sweden failed to have much of an impact.
Wizz Air on Thursday appointed Jourik Hooghe as executive vice president and group chief financial officer, effective from 1 February.
PureTech Health on Thursday said results from a study into a hair loss treatment developed by its affiliate Follica demonstrated a statistically significant 44% improvement in hair count.
European stocks were muted on Thursday morning, as Washington's impeachment drama and rate changes in Sweden failed to have much of an impact.
Versarien on Wednesday received approval for a €350,000 grant from the Graphene Flagship after being selected to participate in an Airbus-led project.
European stocks were restrained at lunchtime on Wednesday as analysts digested data from Germany and the eurozone, with deal news in focus as Fiat Chrysler and Peugeot agreed to a merger.
Shares in Bidstack dived on Wednesday after it cautioned that annual revenue will fall short of targets but added that it is on track to achieve material growth next year.
Touchstar on Wednesday cautioned that long lead times and political uncertainty mean that annual profit and revenue are now expected to be below previous expectations.
Marshall Motor Holdings said it was on course to meet full year expectations despite weakened fourth quarter conditions, while it also announced a £22. 3m acquisition.
IntegraFin boosted its full-year payout on Wednesday as it reported a jump in profits, while the company also lined up a replacement for outgoing chief executive Ian Taylor.